Akorn Promethazine Hydrochloride and Codeine Phosphate Syrup
When a persistent cough disrupts your daily life, finding effective relief becomes a priority. Akorn Promethazine Hydrochloride and Codeine Phosphate Syrup offers a time-tested solution for managing coughs and upper respiratory symptoms. This prescription formulation combines the antihistamine properties of promethazine with the cough-suppressing power of codeine phosphate .
Complete Formula and Composition Details
The classic akorn promethazine hydrochloride mixture incorporates precise active ingredients in every dose. Manufactured originally under NDC 60432-0606-16, each 5 mL measuring volume contains 10 mg of codeine phosphate alongside 6.25 mg of promethazine hcl. The total bottle volume measures 16 oz, equal to 473 ml of oral liquid.
In addition to active compounds, the official formulation features specialized inactive ingredients creating its distinct profile:
- Artificial Boysenberry Flavor for enhanced palatability
- Citric Acid and Sodium Citrate for pH stabilization
- D&C Red No. 33 and FD&C Blue No. 1 coloring agents
- FD&C Yellow No. 6 color accent
- Glycerin and Sucrose for smooth texture and sweetness
- Sodium Benzoate and Sodium Propionate preservatives
- Saccharin Sodium and Purified Water
Product Specifications Table
| Specification Parameter | Official Product Details |
|---|---|
| Brand Name | Akorn |
| Active Composition | Codeine Phosphate (10 mg) / Promethazine HCl (6.25 mg) per 5 mL |
| Dosage Form | Oral Syrup Liquid |
| Container Type & Volume | Bottle (16 oz. / 473 ml) |
| National Drug Code (NDC) | 60432-0606-16 |
| Origin of Product | India / USA Distributed |
| Life Span & Storage | 2 Years Shelf Life (Store at Controlled Room Temperature) |
Therapeutic Uses and Allergy Relief
Patients order akorn promethazine codeine formulations due to its dual action relief mechanism. Promethazine functions as a powerful first generation antihistamine, effectively blocking histamine receptors throughout nasal passages and skin tissues. This process suppresses allergic reactions quickly.
Key therapeutic applications include:
- Seasonal allergy relief, including hay fever management
- Symptom control for continuous runny nose and sneezing
- Reduction of itchy or watery eye irritations
- Soothes hives and persistent itchy skin rashes
- Suppression of acute or spasmodic cough reflex
For detailed pharmacological indexing regarding codeine phosphate syrup combinations, consult the national pharmaceutical listings on DailyMed Library. Furthermore, patients seeking targeted oral therapy options can review our specialized codeine options catalog for additional formulation details.
Correct Dosage Guidelines and Administration
Proper administration ensures safety while maximizing therapeutic outcomes. Standard promethazine hcl adult dosing guidelines recommend 12.5 mg before meals and at bedtime, or a single 25 mg dose taken at bedtime. When combined with codeine for cough suppression, dosage must follow precise medical directions using calibrated measuring devices rather than household spoons.
Storage Instructions and Container Integrity
Maintaining product potency requires controlled environmental storage. Keep the 473ml bottle at room temperature, ideally between 68°F and 77°F (20°C to 25°C). Keep the container tightly closed, shielded from direct sunlight and excessive humidity. Reference regulatory guidance on the FDA Drug Resources database to review safe medication handling procedures.
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